Treatment patterns and outcomes in patients with multiple myeloma in second relapse in Colombia (freedomm): a multicenter observational study - Takeaways - MDSpire

Treatment patterns and outcomes in patients with multiple myeloma in second relapse in Colombia (freedomm): a multicenter observational study

  • By

  • Guillermo Quintero

  • Sandra Aruachan

  • Jair Figueroa Emiliani

  • Kenny Galvez

  • Luis Antonio Salazar

  • Constanza Otero Venegas

  • Diana Buitrago

  • Humberto Martínez-Cordero

  • Juliana Saavedra

  • Maria Fernanda Vargas

  • July 1, 2026

  • 0 min

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  • 1

    The study included 84 Colombian patients with multiple myeloma who experienced a second relapse and initiated third-line therapy between 2013 and 2022.

  • 2

    The median age at diagnosis was 63.5 years, with bone disease and anemia being the most common presenting features among participants.

  • 3

    First-line therapy was primarily bortezomib-based, while second-line treatment shifted towards lenalidomide-based regimens.

  • 4

    In the third-line setting, the overall response rate was 47.1%, with a median overall survival of 27.5 months.

  • 5

    Treatment-emergent adverse events occurred in 11.9% of patients, predominantly moderate and mostly hematologic.

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