Early experience with targeted and combination biopsies in prostate cancer work-up in Denmark from 2012 to 2016

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MRI implementation significantly advanced prostate cancer diagnosis, allowing for targeted biopsies that exclude unnecessary procedures.
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Combining targeted and systematic biopsies (cBx) enhances the detection rate of clinically significant prostate cancer compared to standalone methods.
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In Denmark, from 2012 to 2016, 590 men underwent cBx, with a 67% prostate cancer diagnosis rate, similar to the 67% for standalone biopsies.
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Concordance between cBx and radical prostatectomy pathology was weak, indicating challenges in biopsy accuracy and grading.
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Prostate cancer-specific death rates varied by Gleason grade, with higher grades correlating to increased mortality risk across biopsy strategies.

World Journal Of Urology

by Anna Arendt Blak, Hein V. Stroomberg, Klaus Brasso, Signe Benzon Larsen, Andreas Røder
September 14, 2024

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