Smoking as a correlate of suicidal behavior and self-harm in adolescents with depressive disorders - Takeaways - MDSpire

Smoking as a correlate of suicidal behavior and self-harm in adolescents with depressive disorders

  • By

  • Xiaoxia Wu

  • Lei Ding

  • Jiaquan Liang

  • Lijuan Gao

  • July 1, 2026

  • 0 min

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  • 1

    The study enrolled 2,343 adolescents aged 12–18 with depressive disorders to investigate smoking's association with suicidal behavior and self-harm.

  • 2

    The prevalence of self-harm among participants was 76.0%, while 44.2% reported suicidal behavior, highlighting significant mental health concerns.

  • 3

    Current smokers had 2.74 times higher odds of suicidal behavior, and past quitters had 2.32 times higher odds compared to never smokers.

  • 4

    Current smoking was associated with a 2.31 times increased risk of self-harm, indicating a strong link between smoking and self-injury.

  • 5

    No other demographic or clinical variables, including age and psychiatric diagnosis, were independently associated with suicidal behavior or self-harm.

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