Diagnosis and risk stratification of PI-RADS v2.1 category 3–5 lesions using amide proton transfer imaging

1

Prostate cancer is a prevalent malignancy in men, with increasing incidence and mortality rates necessitating improved diagnostic methods.
2

Multiparametric MRI, particularly using PI-RADS v2.1, helps assess prostate lesions but has a high false positive rate for categories 3-5.
3

Amide proton transfer weighted imaging (APTWI) provides insights into cellular metabolism and may enhance risk stratification of aggressive prostate cancer.
4

This study analyzed 101 patients with PI-RADS v2.1 category 3-5 lesions to evaluate the effectiveness of APTWI combined with ADC and PSAD.
5

The goal is to correlate APTWI parameters with Gleason Scores to improve early diagnosis and treatment strategies for prostate cancer.

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