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1
Small-cell neuroendocrine carcinoma (SCNEC) of the descending colon is rare, particularly in young adults, with an incidence of <0.2% among colorectal tumors.
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2
A 25-year-old male presented with severe abdominal pain, nausea, and vomiting, initially misdiagnosed due to atypical imaging findings.
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3
Initial imaging showed circumferential wall thickening of the descending colon, which was later confirmed as SCNEC through colonoscopy and histopathology.
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4
The patient declined further evaluation initially, leading to significant disease progression and complications, including intestinal obstruction.
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5
This case emphasizes the importance of considering colonic neuroendocrine neoplasms in young patients and the need for early endoscopic biopsy for diagnosis.
