Diplopia as the herald of fulminant myocarditis in undifferentiated connective tissue disease: a case report - Takeaways - MDSpire

Isolated Diplopia as an Initial Indicator of Fulminant Myocarditis in a Case of Undifferentiated Connective Tissue Disease

  • By

  • Yongqi Chen

  • Yinping Li

  • Rui Zhang

  • Xiaokang Liu

  • Jingwen Zhang

  • Ning Zhai

  • Hanheng Zuo

  • Xueying Chen

  • June 4, 2026

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  • 1

    Isolated diplopia can be the sole initial manifestation of fulminant myocarditis associated with undifferentiated connective tissue disease.

  • 2

    A 66-year-old woman presented with diplopia, elevated cardiac enzymes, and no coronary stenosis, leading to a diagnosis of myocarditis.

  • 3

    Endomyocardial biopsy confirmed lymphocytic myocarditis, and serology indicated anti-SSA/Ro52 antibodies, confirming UCTD.

  • 4

    Premature tapering of corticosteroids resulted in relapse and cardiogenic shock, emphasizing the need for careful management.

  • 5

    The case highlights the importance of recognizing atypical presentations of myocarditis and the role of biopsy in treatment guidance.

Original Source(s)

Diplopia as the herald of fulminant myocarditis in undifferentiated connective tissue disease: a case report

  • by Yongqi Chen, Yinping Li, Rui Zhang, Xiaokang Liu, Jingwen Zhang, Ning Zhai, Hanheng Zuo, Xueying Chen

  • June 4, 2026

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