Systemic Immune Responses in Patients with Spine Surgery Related Infections - Takeaways - MDSpire

Systemic Immune Responses in Patients with Spine Surgery Related Infections

  • By

  • Fehrenbach, Pia

  • Lang, Siegmund

  • Gocević, Maja

  • Kwant, Puk

  • Haschtmann, Daniel

  • Fekete, Tamas F.

  • Menzel, Ursula

  • De Jong, Esther Christina

  • Moriarty, Fintan Thomas

  • Grad, Sibylle

  • Loibl, Markus

  • May 4, 2026

  • 0 min

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  • 1

    Surgical site infections (SSIs) are significant complications following spine surgery.

  • 2

    The immune responses in postoperative infections of the spine are poorly understood compared to other infections.

  • 3

    The study analyzed immune cell profiles in patients with infections after spinal surgery versus non-infected controls.

  • 4

    Significant differences in immune cell clusters were identified, with decreased innate immune cells in infected patients.

  • 5

    Increased levels of HLA-DR+ CD4+ T cells were noted in patients with infections, indicating altered immune profiles.

Original Source(s)

Systemic Immune Responses in Patients with Spine Surgery Related Infections

  • by Fehrenbach, Pia , Lang, Siegmund , Gocević, Maja , Kwant, Puk , Haschtmann, Daniel , Fekete, Tamas F., Menzel, Ursula , De Jong, Esther Christina, Moriarty, Fintan Thomas, Grad, Sibylle , Loibl, Markus

  • May 4, 2026

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