Coexistence of Multiple Superficial Lipomatous Nevi and a Verrucous Nevus: A Case Study - Takeaways - MDSpire

Coexistence of Multiple Superficial Lipomatous Nevi and a Verrucous Nevus: A Case Study

  • By

  • Lixiu Chen

  • Wenjun Zeng

  • Guihong Zhu

  • Kun Zhang

  • April 24, 2026

  • 0 min

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  • 1

    Nevus lipomatosus cutaneous superficialis (NLCS) is a rare benign hamartoma characterized by ectopic mature adipocytes in the dermis.

  • 2

    Verrucous epidermal nevus (VEN) is a common epidermal hamartoma presenting with verrucous hyperplasia and is characterized histologically by epidermal papillomatosis.

  • 3

    The coexistence of NLCS and VEN in a single patient is exceedingly rare, suggesting a potential common developmental origin.

  • 4

    A 20-year-old male presented with multiple skin-colored lesions on his left lower back, diagnosed as coexistent NLCS and VEN after histopathological examination.

  • 5

    This case emphasizes the need for clinicians to consider combined hamartomas when encountering linear skin lesions and to perform multiple-site biopsies.

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