Risk factors for a severe disease course in children with SARS-COV-2 infection following hematopoietic cell transplantation in the pre-Omicron period: a prospective multinational Infectious Disease Working Party from the European Society for Blood and Marrow Transplantation group (EBMT) and the Spanish Group of Hematopoietic Stem Cell Transplantation (GETH) study - Takeaways - MDSpire

Risk factors for a severe disease course in children with SARS-COV-2 infection following hematopoietic cell transplantation in the pre-Omicron period: a prospective multinational Infectious Disease Working Party from the European Society for Blood and Marrow Transplantation group (EBMT) and the Spanish Group of Hematopoietic Stem Cell Transplantation (GETH) study

  • By

  • Dina Averbuch

  • Rafael de la Camara

  • Gloria Tridello

  • Nina Simone Knelange

  • Tatiana A. Bykova

  • Marianne Ifversen

  • Veronika Dobsinska

  • Mouhab Ayas

  • Amir Ali Hamidieh

  • Herbert Pichler

  • Antonio Perez-Martinez

  • Simone Cesaro

  • Mikael Sundin

  • Isabel Badell

  • Peter Bader

  • Jan-Erik Johansson

  • Oana Mirci-Danicar

  • Petr Sedlacek

  • Catherine Paillard

  • Brenda Gibson

  • Sarah Lawson

  • Nicolaus Kroeger

  • Selim Corbacioglu

  • Malgorzata Mikulska

  • Jose Luis Piñana

  • Jan Styczynski

  • Per Ljungman

  • February 27, 2023

  • 0 min

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  • 1

    Children with underlying diseases, including those who underwent hematopoietic cell transplantation, are at higher risk for severe COVID-19.

  • 2

    The study analyzed data from 89 children with SARS-CoV-2 infection following hematopoietic cell transplantation across 28 centers in 18 countries.

  • 3

    Common clinical manifestations of COVID-19 in these children included fever, cough, and upper respiratory symptoms, with 42% being asymptomatic.

  • 4

    Ten percent of children required ICU care, all of whom were neutropenic and receiving immunosuppressive therapy at the time of diagnosis.

  • 5

    The study highlights the need for further research on risk factors associated with severe COVID-19 in pediatric hematopoietic cell transplantation recipients.

Original Source(s)

Risk factors for a severe disease course in children with SARS-COV-2 infection following hematopoietic cell transplantation in the pre-Omicron period: a prospective multinational Infectious Disease Working Party from the European Society for Blood and Marrow Transplantation group (EBMT) and the Spanish Group of Hematopoietic Stem Cell Transplantation (GETH) study

  • by Dina Averbuch, Rafael de la Camara, Gloria Tridello, Nina Simone Knelange, Tatiana A. Bykova, Marianne Ifversen, Veronika Dobsinska, Mouhab Ayas, Amir Ali Hamidieh, Herbert Pichler, Antonio Perez-Martinez, Simone Cesaro, Mikael Sundin, Isabel Badell, Peter Bader, Jan-Erik Johansson, Oana Mirci-Danicar, Petr Sedlacek, Catherine Paillard, Brenda Gibson, Sarah Lawson, Nicolaus Kroeger, Selim Corbacioglu, Malgorzata Mikulska, Jose Luis Piñana, Jan Styczynski, Per Ljungman

  • February 27, 2023

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