Efficacy of a radiofrequency thermocoagulation strategy targeting the propagation network in MRI-negative post-encephalitic insular epilepsy: a case report - Takeaways - MDSpire

Efficacy of a radiofrequency thermocoagulation strategy targeting the propagation network in MRI-negative post-encephalitic insular epilepsy: a case report

  • By

  • Tomotaka Ishizaki

  • Satoshi Maesawa

  • Shun Yamamoto

  • Takahiro Suzuki

  • Hajime Hamasaki

  • Takafumi Tanei

  • Ryuta Saito

  • August 27, 2025

  • 0 min

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  • 1

    Post-encephalitic epilepsy often resists treatment, particularly in MRI-negative cases where localizing the epileptic focus is difficult.

  • 2

    A case of drug-resistant insular epilepsy was treated with radiofrequency thermocoagulation to disconnect the propagation network, achieving favorable outcomes.

  • 3

    Preoperative evaluations included MRI, VEEG, and SEEG, which identified seizure origins and propagation patterns despite no visible lesions.

  • 4

    The targeted disconnection strategy utilized diffusion tensor imaging to visualize fiber tracts, avoiding damage to critical areas.

  • 5

    Radiofrequency thermocoagulation was performed under local anesthesia, resulting in 44 coagulation lesions to disrupt the epileptic propagation network.

Original Source(s)

Efficacy of a radiofrequency thermocoagulation strategy targeting the propagation network in MRI-negative post-encephalitic insular epilepsy: a case report

  • by Tomotaka Ishizaki, Satoshi Maesawa, Shun Yamamoto, Takahiro Suzuki, Hajime Hamasaki, Takafumi Tanei, Ryuta Saito

  • August 27, 2025

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