Age-stratified clinical characteristics of hand, foot, and mouth disease in children and its guiding value for diagnosis and treatment - Takeaways - MDSpire

Age-stratified clinical characteristics of hand, foot, and mouth disease in children and its guiding value for diagnosis and treatment

  • By

  • Shuzhen Dai

  • Xiaoling Hu

  • Meihong Lin

  • Wenwen Chen

  • Liping Xu

  • July 7, 2026

  • 0 min

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  • 1

    The study analyzed 216 hospitalized children with hand, foot, and mouth disease (HFMD) across four age groups.

  • 2

    Children aged 1–3 years comprised 62.76% of the cohort, with 88.43% of patients under 4 years old.

  • 3

    Neonates exhibited longer hospital stays and significant cerebrospinal fluid abnormalities compared to older children.

  • 4

    Convulsions were most common in children aged 1–3 years, while intracranial hypertension was more frequent in those over 3 years.

  • 5

    The findings highlight the need for age-stratified diagnostic and management strategies for HFMD in pediatric patients.

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