Prevalence of Meibomian Gland Dysfunction in the Upper Eyelid Among Postmenopausal Women with Primary Acquired Nasolacrimal Duct Obstruction - Takeaways - MDSpire
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Prevalence of Meibomian Gland Dysfunction in the Upper Eyelid Among Postmenopausal Women with Primary Acquired Nasolacrimal Duct Obstruction

  • By

  • Haili Jin

  • Xianjie Chen

  • Yin Liu

  • October 29, 2025

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  • 1

    Primary acquired nasolacrimal duct obstruction (PANDO) predominantly affects postmenopausal women, with a female-to-male incidence ratio of up to 3:1.

  • 2

    Meibomian gland dysfunction (MGD) is a significant factor in evaporative dry eye disease, particularly in postmenopausal individuals.

  • 3

    Patients with lacrimal duct obstruction may experience dry eye symptoms even after successful surgical intervention.

  • 4

    This study investigates the involvement of meibomian glands in the upper and lower eyelids among postmenopausal women with PANDO.

  • 5

    Understanding the relationship between meibomian gland parameters and tear film function may inform targeted therapeutic strategies for PANDO.

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