Case Report: Sellar collision tumor consisting of pituitary adenoma and craniopharyngioma, with literature review - Takeaways - MDSpire

Case Report: Sellar collision tumor consisting of pituitary adenoma and craniopharyngioma, with literature review

  • By

  • Junhao Jin

  • Bin Gu

  • Guojian Wu

  • Jun Kong

  • Huilin Cheng

  • Xiaoying Wei

  • July 6, 2026

  • 0 min

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  • 1

    Collision tumors of pituitary adenoma and craniopharyngioma are extremely rare, with few documented cases in the literature.

  • 2

    A 64-year-old female presented with symptoms of fatigue, anorexia, and severe electrolyte disturbances, indicating pan-hypopituitarism.

  • 3

    Preoperative MRI revealed a large sellar lesion, classified as Hardy Grade B and Knosp Grade 2, compressing the optic chiasm.

  • 4

    During surgery, the tumor exhibited a tough, fibrous consistency with no discernible boundary between the adenoma and craniopharyngioma.

  • 5

    Postoperative pathology confirmed a collision of Null-cell adenoma and Adamantinomatous craniopharyngioma, highlighting diagnostic challenges.

Original Source(s)

Case Report: Sellar collision tumor consisting of pituitary adenoma and craniopharyngioma, with literature review

  • by Junhao Jin, Bin Gu, Guojian Wu, Jun Kong, Huilin Cheng, Xiaoying Wei

  • July 6, 2026

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