Peak-MELD scores, a disease trajectory associated with reduced access to liver transplantation - Takeaways - MDSpire

Peak-MELD scores, a disease trajectory associated with reduced access to liver transplantation

  • By

  • Paul Jamme

  • Julian Allgeier

  • Dionysios Koliogiannis

  • Markus Guba

  • Christian M. Lange

  • June 26, 2026

  • 0 min

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  • 1

    The MELD score is the primary allocation tool for liver transplantation in the Eurotransplant region.

  • 2

    In a study of 109 patients, 11% experienced a peak-MELD trajectory, linked to lower transplantation rates.

  • 3

    Patients with peak-MELD scores had longer median waiting times for transplantation compared to those without.

  • 4

    Infections were the predominant cause of waitlist status changes in patients with peak-MELD scores.

  • 5

    The study suggests that transient MELD increases due to infections may reduce access to liver transplantation.

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