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1
Atrial fibrillation (AF) significantly increases the risk of ischemic stroke, with oral anticoagulation (OAC) reducing this risk by 60%-70%.
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2
Continuous rhythm monitoring has revealed a spectrum of atrial arrhythmias, challenging the traditional binary AF diagnosis and treatment approach.
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3
AF burden, defined as the proportion of monitored time spent in AF, is associated with higher risks of ischemic stroke and systemic embolism.
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4
Low AF burden patients generally experience low absolute event rates, raising questions about the net clinical benefit of OAC in this group.
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5
Current evidence suggests that AF burden alone is insufficient for anticoagulation decisions, as it interacts with thromboembolic and bleeding risks.
