The Role of Neutrophil-to-Lymphocyte Ratio in Severe Neonatal SARS-CoV-2 Infections: Links to Changes in Lymphocyte Subpopulations - Takeaways - MDSpire

The Role of Neutrophil-to-Lymphocyte Ratio in Severe Neonatal SARS-CoV-2 Infections: Links to Changes in Lymphocyte Subpopulations

  • By

  • Guangliang Bi

  • Qingyan Xiao

  • Jie He

  • Shuzhe Xiao

  • Jie Yang

  • February 26, 2026

  • 0 min

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  • 1

    Emerging SARS-CoV-2 variants, particularly from the Omicron family, exhibit enhanced transmissibility and immune evasion, impacting neonatal health.

  • 2

    Neonates are at increased risk for severe complications from SARS-CoV-2 due to their immature immune systems and limited maternal antibody transfer.

  • 3

    The study investigates the association between neutrophil-to-lymphocyte ratio (NLR) and disease severity in SARS-CoV-2-positive term neonates.

  • 4

    Neonates diagnosed with COVID-19 were compared to healthy controls to assess changes in lymphocyte subpopulations and NLR.

  • 5

    Severe illness in neonates was defined by specific clinical and laboratory criteria, including respiratory distress and abnormal blood counts.

Original Source(s)

The Role of Neutrophil-to-Lymphocyte Ratio in Severe Neonatal SARS-CoV-2 Infections: Links to Changes in Lymphocyte Subpopulations

  • by Guangliang Bi, Qingyan Xiao, Jie He, Shuzhe Xiao, Jie Yang

  • February 26, 2026

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