Overview of Human Biomonitoring Efforts for Beauvericin and Enniatins

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Beauvericin (BEA) and enniatins (ENNs) are emerging mycotoxins produced by Fusarium species and are prevalent in food and feed globally.
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BEA and ENNs exhibit cytotoxic effects in vitro at low concentrations, but BEA lacks genotoxic activity according to recent evaluations.
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Dietary exposure to BEA and ENNs primarily comes from grains and grain-derived products, with acute exposures significantly below mouse LD50 values.
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Human biomonitoring (HBM) has been utilized to detect BEA and ENNs in biological samples, providing insights into their internal concentrations.
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Current analytical methods for detecting BEA and ENNs in human samples involve liquid chromatography and mass spectrometry, with ongoing research to improve risk assessment.

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