Acquired reactive perforating collagenosis in a patient with multiple comorbidities: a case report from Palestine - Takeaways - MDSpire

Acquired reactive perforating collagenosis in a patient with multiple comorbidities: a case report from Palestine

  • By

  • Majd Mohsen

  • Eman Jaber

  • Qais Naserallah

  • Montaser Badran

  • Sameer Mtour

  • Sami Bannoura

  • Rabee Adwan

  • June 26, 2026

  • 0 min

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  • 1

    Acquired reactive perforating collagenosis (ARPC) is a rare dermatologic condition associated with systemic diseases like diabetes and chronic kidney disease.

  • 2

    A 55-year-old male with multiple health issues, including type 2 diabetes and chronic renal failure, was diagnosed with ARPC after presenting with skin lesions.

  • 3

    Histopathological examination revealed cup-shaped epidermal invaginations and transepidermal extrusion of modified collagen, confirming the diagnosis of ARPC.

  • 4

    The patient received treatment including topical corticosteroids and systemic medications, but showed minimal improvement in pruritus and no change in skin lesions.

  • 5

    This case represents the first reported instance of ARPC in Palestine, highlighting the need for awareness among clinicians regarding this condition.

Original Source(s)

Acquired reactive perforating collagenosis in a patient with multiple comorbidities: a case report from Palestine

  • by Majd Mohsen, Eman Jaber, Qais Naserallah, Montaser Badran, Sameer Mtour, Sami Bannoura, Rabee Adwan

  • June 26, 2026

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