Role of Peripheral Eosinophil Counts in Predicting Subclinical Lung Dysfunction in Chronic Rhinosinusitis and Their Correlation with Coagulation Markers - Takeaways - MDSpire

Role of Peripheral Eosinophil Counts in Predicting Subclinical Lung Dysfunction in Chronic Rhinosinusitis and Their Correlation with Coagulation Markers

  • By

  • Fengxia Yang

  • Yuqiao Zhang

  • Xiyuan Yan

  • Juanjuan Han

  • Ruixia Ma

  • March 3, 2026

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  • 1

    Chronic rhinosinusitis (CRS) affects 11-14% of the global population and is linked to subclinical pulmonary impairment in 30-50% of patients.

  • 2

    Subclinical pulmonary impairment in CRS can lead to serious respiratory conditions like asthma and COPD, often going undetected due to asymptomatic early changes.

  • 3

    The study aimed to investigate the relationship between peripheral eosinophil counts and subclinical lung dysfunction in non-asthmatic CRS patients.

  • 4

    A retrospective analysis was conducted on 450 CRS patients, comparing their eosinophil levels and coagulation markers to a control group of healthy individuals.

  • 5

    Identifying eosinophil counts as potential biomarkers could facilitate early intervention to prevent progressive lung disease in CRS patients.

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