The impact of sociodemographic background on clinical presentation of high-grade gliomas: a multi-institutional retrospective analysis - Takeaways - MDSpire

The impact of sociodemographic background on clinical presentation of high-grade gliomas: a multi-institutional retrospective analysis

  • By

  • Sayak R. Ghosh

  • Anne R. Lally

  • Isabella L. Pecorari

  • Joshua Reynolds

  • Alexander Ledet

  • Sabrina Begley

  • Elizabeth Juarez Diaz

  • Eric Zhu

  • Karan Joseph

  • Kyle McGeehan MPhil

  • Michael Schulder

  • Tanner Johanns

  • Yonah C. Ziemba

  • Vijay Agarwal

  • March 25, 2025

  • 0 min

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  • 1

    High-grade gliomas (HGG) account for 80.7% of primary brain malignancies, with a median survival of 12-72 months depending on tumor grade.

  • 2

    Clinical presentation of HGG varies by tumor location and size, with symptoms categorized as generalized or focal, including headaches and seizures.

  • 3

    Incidence of gliomas is highest among European Americans, with a lifetime risk twice that of African Americans and 25% higher than Hispanic Americans.

  • 4

    White patients with HGG are diagnosed at an older age and present more with cognitive deficits, while Black and Hispanic patients show more severe symptoms.

  • 5

    This study highlights the need for further research into sociodemographic factors affecting HGG presentation and their implications for diagnosis and treatment.

Original Source(s)

The impact of sociodemographic background on clinical presentation of high-grade gliomas: a multi-institutional retrospective analysis

  • by Sayak R. Ghosh, Anne R. Lally, Isabella L. Pecorari, Joshua Reynolds, Alexander Ledet, Sabrina Begley, Elizabeth Juarez Diaz, Eric Zhu, Karan Joseph, Kyle McGeehan MPhil, Michael Schulder, Tanner Johanns, Yonah C. Ziemba, Vijay Agarwal

  • March 25, 2025

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