GCxGC Detective Stories: Not Just a Pretty Face

Mariosimone Zoccali discusses the evolution of GCxGC, which he describes as “one of the most exciting stories in separation science”

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GC×GC has evolved into a central analytical platform, increasingly used across diverse fields for real analytical decisions.
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The technique is now valued for its peak capacity, identification, fingerprinting, classification, and target/non-target workflows.
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Advancements in modulators and data-processing tools have made GC×GC more accessible and practical for routine laboratories.
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GC×GC excels in complex mixtures, particularly when combined with mass spectrometry, enhancing identification confidence.
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Younger scientists are driving progress in GC×GC, contributing to innovative applications in areas like PFAS screening and food authenticity.

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