Risk factors and intervention strategies for lower extremity deep vein thrombosis after intravenous thrombolysis for acute ischemic stroke

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The study analyzed 197 acute ischemic stroke patients treated with intravenous thrombolysis between January 2021 and April 2024.
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Absence of early pharmacological thromboprophylaxis was linked to a higher incidence of in-hospital lower extremity DVT, with 30.4% of non-prophylaxis patients developing DVT.
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Factors associated with non-initiation of early prophylaxis included atrial fibrillation, higher NIHSS scores, prolonged bed rest, and elevated D-dimer levels.
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Among the 197 patients, 118 (59.9%) received early prophylaxis, while 79 (40.1%) did not, highlighting a significant prevention gap.
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The study suggests a risk-treatment paradox where patients at higher thrombotic risk were less likely to receive early prophylaxis due to concerns about hemorrhagic transformation.

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