Treating socket discharge and discomfort: a crossover randomised trial of vitamin A ointment, low-dose steroid eyedrops and artificial tears - Takeaways - MDSpire
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Comparative Efficacy of Vitamin A Ointment, Low-Dose Steroid Eye Drops, and Artificial Tears for Managing Socket Discharge and Discomfort: A Randomized Crossover Study

  • By

  • Arthur Yu Xiang Liu

  • Stijn W Van Der Meeren

  • Adriaan D Coumou

  • Rachel Kalmann

  • Dyonne T Hartong

  • October 1, 2026

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  • 1

    The study is the first systematic comparison of vitamin A ointment, low-dose steroid eye drops, and artificial tears for socket discharge.

  • 2

    Vitamin A ointment significantly outperformed other treatments in reducing irritation and discharge in anophthalmic patients.

  • 3

    Chronic mucopurulent discharge and discomfort are common issues faced by patients with ocular prostheses.

  • 4

    The randomized crossover trial design allowed each participant to serve as their own control, enhancing treatment comparison reliability.

  • 5

    Results from this study may inform personalized management approaches for ocular prosthesis complications.

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