Efficacy Assessment of Radiotherapy Alone Versus Combined Surgery and Radiotherapy for Ipsilateral Supraclavicular Lymph Node Metastasis in Breast Cancer: A Retrospective Study with Eight-Year Follow-Up Utilizing Propensity Score Matching - Takeaways - MDSpire

Efficacy Assessment of Radiotherapy Alone Versus Combined Surgery and Radiotherapy for Ipsilateral Supraclavicular Lymph Node Metastasis in Breast Cancer: A Retrospective Study with Eight-Year Follow-Up Utilizing Propensity Score Matching

  • By

  • Chao Wei

  • Shuhua Zhou

  • Longyu Zhu

  • Jie Kong

  • Zimeng Gao

  • Danyang Wang

  • Deyou Kong

  • Andu Zhang

  • Shuo Pan

  • Kaiye Du

  • Dongxing Shen

  • Jun Zhang

  • Zhikun Liu

  • December 26, 2025

  • 0 min

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  • 1

    Breast cancer with ipsilateral supraclavicular lymph node metastasis (ISLM) is classified as locally advanced and indicates a poor prognosis.

  • 2

    The study analyzed the efficacy of radiotherapy alone versus combined surgery and radiotherapy for patients with sISLM breast cancer.

  • 3

    A total of 326 female patients with sISLM were included, with 238 receiving radiotherapy alone and 88 undergoing surgery plus radiotherapy.

  • 4

    The study aimed to explore optimal local treatment strategies for sISLM breast cancer to improve clinical decision-making.

  • 5

    Advancements in systemic treatments have improved the prognosis for ISLM breast cancer, but local management strategies remain debated.

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