Documented risk-based antithrombotic management and 30-day outcomes after endoscopic hemostasis for non-variceal upper gastrointestinal bleeding: a retrospective cohort study - Takeaways - MDSpire
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Assessment of Risk-Adjusted Antithrombotic Strategies and 30-Day Clinical Outcomes Following Endoscopic Treatment for Non-Variceal Upper Gastrointestinal Bleeding: A Retrospective Cohort Analysis

  • By

  • Xiaoyun Zhao

  • Li Wang

  • Jianyi Li

  • August 25, 2026

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  • 1

    The study assessed the impact of adherence to a risk-based antithrombotic management framework on 30-day outcomes after endoscopic treatment for NVUGIB.

  • 2

    Adherent patients showed significantly lower rates of rebleeding (5.2%) and net adverse clinical events (12.0%) compared to non-adherent patients (17.8% and 34.0%, respectively).

  • 3

    The study included 150 index admissions, with 100 patients documented as adherent and 50 as non-adherent to the management framework.

  • 4

    Overall, 9.2% of patients experienced rebleeding, 10.7% had thromboembolism, and 19.3% experienced net adverse clinical events within 30 days.

  • 5

    The findings suggest that documented adherence to a structured management framework correlates with fewer adverse events in the short term.

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