Case Report: Voglibose-induced persistent leukopenia in a patient with type 2 diabetes - Takeaways - MDSpire

Case Report: Voglibose-induced persistent leukopenia in a patient with type 2 diabetes

  • By

  • Jing-wen Guo

  • Jin-hong Yan

  • Li-shuang Chang

  • Shuang Cai

  • Ya-qiu Jiang

  • Fen-qin Chen

  • June 4, 2026

  • 0 min

Share

  • 1

    A 71-year-old male with type 2 diabetes developed persistent leukopenia after five years of voglibose therapy.

  • 2

    Bone marrow biopsy revealed hypoplasia, and conventional treatments for leukopenia were ineffective.

  • 3

    Switching from voglibose to acarbose resulted in a significant increase in the patient's white blood cell count.

  • 4

    The Naranjo score of 7 indicated a probable causal relationship between voglibose and leukopenia.

  • 5

    This case highlights the need for medication review in diabetic patients with unexplained cytopenia.

Original Source(s)

Case Report: Voglibose-induced persistent leukopenia in a patient with type 2 diabetes

  • by Jing-wen Guo, Jin-hong Yan, Li-shuang Chang, Shuang Cai, Ya-qiu Jiang, Fen-qin Chen

  • June 4, 2026

Related Content

Based on Propensity Matching Scores: Comparison of the Mid-term Outcomes of Two Bariatric Surgeries for the Treatment of Obesity and its Complications

Endocrine Dysfunction in Primary Mitochondrial Diseases

Long-Term Outcomes of One-Anastomosis Gastric Bypass: A Systematic Review of Studies with at Least 10 Years of Follow-Up