Allergenicity assessment of novel foods - lessons from immune endotyping of food-allergic patients - Takeaways - MDSpire

Allergenicity assessment of novel foods - lessons from immune endotyping of food-allergic patients

  • By

  • Isabela Assugeni

  • Melike Gezen

  • Gül Duman

  • Naphisabet Wanniang

  • Françoise Codreanu-Morel

  • Gabriele Gadermaier

  • Theresa-Maria Boehm

  • Annette Kuehn

  • June 10, 2026

  • 0 min

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  • 1

    Novel foods (NF) are defined as foods not commonly consumed in Europe before May 1997 and require safety demonstration before market introduction.

  • 2

    Food allergy (FA) affects up to 10% of the global population, with increasing prevalence particularly among children.

  • 3

    Current guidelines for NF allergenicity assessment focus on known allergens but provide limited direction for unknown allergenic potential.

  • 4

    Immune endotyping can differentiate between food allergy, asymptomatic IgE sensitization, and healthy states based on immune cell reactivity.

  • 5

    A recent review indicated that allergenicity risk was likely in 50% of approved novel foods from 2018 to 2023, highlighting gaps in predictive methods.

Original Source(s)

Allergenicity assessment of novel foods - lessons from immune endotyping of food-allergic patients

  • by Isabela Assugeni, Melike Gezen, Gül Duman, Naphisabet Wanniang, Françoise Codreanu-Morel, Gabriele Gadermaier, Theresa-Maria Boehm, Annette Kuehn

  • June 10, 2026

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