The Ratio of Creatinine to Body Weight as a Predictor of Mortality in Critically Ill Heart Failure Patients: Insights from a Retrospective Analysis of the MIMIC-IV Database - Takeaways - MDSpire

The Ratio of Creatinine to Body Weight as a Predictor of Mortality in Critically Ill Heart Failure Patients: Insights from a Retrospective Analysis of the MIMIC-IV Database

  • By

  • Dunlin Fang

  • Yanyi Huang

  • Jian Huang

  • Wanchun Hu

  • Changchang Zhang

  • Xing Liu

  • Zhenyu Shi

  • January 20, 2026

  • 0 min

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  • 1

    Heart failure (HF) is a major public health issue, with a global prevalence of 0.1% to 6.7% and an annual mortality rate of approximately 10%.

  • 2

    The creatinine-to-weight ratio (CWR) has shown a significant correlation with mortality in various diseases, including cardiovascular disorders.

  • 3

    Critically ill HF patients experience markedly higher mortality rates compared to stable counterparts, highlighting the need for reliable risk assessment tools.

  • 4

    The study utilized the MIMIC-IV database to analyze data from 4,371 HF patients, focusing on the prognostic value of CWR.

  • 5

    Elevated creatinine levels are associated with increased mortality risk in cardiovascular diseases and chronic heart failure.

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