Case Report: Brugada syndrome uncovered by delivery in a 32-year-old patient - Takeaways - MDSpire
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Delivery Reveals Brugada Syndrome in a 32-Year-Old Primigravida: A Case Study

  • By

  • Peng Liu

  • Ruilong Gao

  • Yaliu Yang

  • Zhengqin Zhai

  • Yifeng Zhou

  • September 9, 2026

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  • 1

    A 32-year-old primigravida experienced ventricular fibrillation shortly after an uncomplicated vaginal birth.

  • 2

    The patient's ECG revealed a spontaneous type 1 Brugada syndrome pattern following resuscitation.

  • 3

    No structural heart disease was found, and genetic testing did not identify pathogenic variants associated with Brugada syndrome.

  • 4

    Multiple factors, including epidural ropivacaine, postpartum autonomic instability, and electrolyte imbalance, likely unmasked latent Brugada syndrome.

  • 5

    An implantable cardioverter-defibrillator was placed for secondary prevention, and no arrhythmic episodes were recorded during 18 months of follow-up.

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