High-Intensity Transcranial Alternating Current Stimulation for Emotion Regulation and Attentional Bias in - Takeaways - MDSpire

High-Intensity Transcranial Alternating Current Stimulation for Emotion Regulation and Attentional Bias in

  • By

  • Tiejun Kang

  • Xuan Zhao

  • Xiaoning Huo

  • Xuan Liu

  • Yannan Wang

  • Xinlin Wang

  • Xiaobin Ding

  • Heng Wu

  • June 9, 2026

  • 0 min

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  • 1

    Nonsuicidal self-injury (NSSI) is prevalent among adolescents, particularly females, and is linked to major depressive disorder (MDD).

  • 2

    Deficits in emotion regulation and attentional bias toward NSSI cues are critical factors that sustain and worsen NSSI behaviors in adolescents.

  • 3

    High-intensity transcranial alternating current stimulation (HI-tACS) may improve emotion regulation and attentional mechanisms in adolescents with MDD and NSSI.

  • 4

    The randomized clinical trial aims to evaluate the clinical potential and safety of 77.5 Hz HI-tACS targeting the prefrontal cortex.

  • 5

    Participants aged 12 to 18 with MDD and NSSI underwent 30 stimulation sessions over 3 weeks, with a double-blind, sham-controlled design.

Original Source(s)

High-Intensity Transcranial Alternating Current Stimulation for Emotion Regulation and Attentional Bias in

  • by Tiejun Kang, Xuan Zhao, Xiaoning Huo, Xuan Liu, Yannan Wang, Xinlin Wang, Xiaobin Ding, Heng Wu

  • June 9, 2026

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