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Sugar-Sweetened Beverages May Raise Risk of Hepatic Cancer Subtypes
In a pooled analysis of more than 1.5 million patients, sugar-sweetened beverages were associated with higher risks of HCC and ICC, while artificially-sweetened beverages showed no independent association with hepatic cancer.
Higher consumption of sugar-sweetened beverages is associated with increased risks of hepatocellular carcinoma and intrahepatic cholangiocarcinoma.
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The study analyzed data from over 1.5 million patients enrolled in 11 prospective cohort studies across the United States and Europe.
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Each additional daily sugar-sweetened beverage was linked to a 10% higher likelihood of hepatocellular carcinoma and a 15% higher likelihood of intrahepatic cholangiocarcinoma.
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Artificially-sweetened beverage intake showed no association with hepatic cancer risk after adjusting for demographic and lifestyle factors.
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Limitations of the study include reliance on self-reported beverage consumption and incomplete data on hepatitis virus infection status.
