Sciatic nerve atrophy as a predictor of impaired wound healing in patients with chronic limb-threatening ischemia following endovascular therapy: A prospective pilot study - Takeaways - MDSpire

Sciatic nerve atrophy as a predictor of impaired wound healing in patients with chronic limb-threatening ischemia following endovascular therapy: A prospective pilot study

  • By

  • Xinzhi Yang

  • Gong Cheng

  • Pengyu Li

  • Ziguang Yan

  • Bihui Zhang

  • Kang She

  • Jue Zhang

  • Guochen Niu

  • Min Yang

  • June 15, 2026

  • 0 min

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  • 1

    Chronic limb-threatening ischemia (CLTI) is a severe form of peripheral artery disease associated with significant wound healing complications.

  • 2

    Endovascular therapy (EVT) is a minimally invasive treatment option for CLTI that can facilitate wound healing and limb salvage.

  • 3

    Sciatic nerve atrophy (SNA) has been identified as a potential predictive factor for adverse wound outcomes following EVT in CLTI patients.

  • 4

    The study evaluated patients with CLTI and lower-limb tissue loss to assess the relationship between SNA and wound healing rates.

  • 5

    Wound assessment utilized the WIfI staging system and the Pressure Ulcer Scale for Healing (PUSH) score to measure outcomes post-EVT.

Original Source(s)

Sciatic nerve atrophy as a predictor of impaired wound healing in patients with chronic limb-threatening ischemia following endovascular therapy: A prospective pilot study

  • by Xinzhi Yang, Gong Cheng, Pengyu Li, Ziguang Yan, Bihui Zhang, Kang She, Jue Zhang, Guochen Niu, Min Yang

  • June 15, 2026

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