Determinants of survival after re-resection for recurrent glioblastoma: a meta-analysis - Takeaways - MDSpire

Determinants of survival after re-resection for recurrent glioblastoma: a meta-analysis

  • By

  • Manuel V. Baby

  • Rithvik M. Narendranath

  • Symriti Kaur-Paneser

  • Daniele S. C. Ramsay

  • Hariharan Subbiah Ponniah

  • Srikar R. Namireddy

  • Ahmed Salih

  • Ahkash Thavarajasingam

  • Daniel Scurtu

  • Andreas Kramer

  • Veit Stöcklein

  • Darius Kalasauskas

  • Dragan Jankovic

  • Florian Ringel

  • Santhosh G. Thavarajasingam

  • January 13, 2026

  • 0 min

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  • 1

    Glioblastoma is the most common primary malignant brain tumor, with an annual incidence of approximately 3.2 per 100,000 people.

  • 2

    The standard initial treatment for glioblastoma includes maximal safe resection followed by radiotherapy and temozolomide, extending median survival by about 2.5 months.

  • 3

    Re-resection for recurrent glioblastoma is considered in 10% to 30% of patients, but its role and survival benefit remain controversial.

  • 4

    This meta-analysis aims to quantitatively assess prognostic factors influencing survival after re-resection for recurrent glioblastoma.

  • 5

    A sensitivity analysis focused on IDH-wildtype patients was conducted to ensure consistency in evaluating prognostic factors.

Original Source(s)

Determinants of survival after re-resection for recurrent glioblastoma: a meta-analysis

  • by Manuel V. Baby, Rithvik M. Narendranath, Symriti Kaur-Paneser, Daniele S. C. Ramsay, Hariharan Subbiah Ponniah, Srikar R. Namireddy, Ahmed Salih, Ahkash Thavarajasingam, Daniel Scurtu, Andreas Kramer, Veit Stöcklein, Darius Kalasauskas, Dragan Jankovic, Florian Ringel, Santhosh G. Thavarajasingam

  • January 13, 2026

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