Metastatic malignant melanoma presenting as bilateral acute mastitis in a lactating woman: a case report and literature review - Takeaways - MDSpire

Metastatic malignant melanoma presenting as bilateral acute mastitis in a lactating woman: a case report and literature review

  • By

  • Zilin Wang

  • Shaowu Zeng

  • Qiaorong Zhou

  • Jujiang Guo

  • July 6, 2026

  • 0 min

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  • 1

    Bilateral acute mastitis can be a rare presentation of metastatic malignant melanoma, complicating diagnosis in postpartum women.

  • 2

    The case involved a 36-year-old woman misdiagnosed with severe lactational mastitis, later found to have diffusely metastatic melanoma.

  • 3

    Metastatic melanoma to the breast is uncommon, accounting for only 1.3% to 2.7% of reported metastatic cases.

  • 4

    The patient's aggressive disease course included failure to respond to targeted therapy, immunotherapy, and chemotherapy.

  • 5

    This case highlights the need for thorough history-taking and suspicion of metastatic disease in atypical breast presentations.

Original Source(s)

Metastatic malignant melanoma presenting as bilateral acute mastitis in a lactating woman: a case report and literature review

  • by Zilin Wang, Shaowu Zeng, Qiaorong Zhou, Jujiang Guo

  • July 6, 2026

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