Radical nephroureterectomy vs kidney sparing surgery for upper tract urothelial carcinoma in solitary kidney patients: a multi-institutional analysis of the ROBUUST 2.0 registry

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The study analyzes outcomes of solitary kidney patients with upper tract urothelial carcinoma undergoing radical nephroureterectomy (RNU) or kidney sparing surgery (KSS).
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Among 3,216 patients, only 51 had a solitary kidney, with 39 undergoing RNU and 12 undergoing KSS, highlighting the rarity of this clinical scenario.
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RNU patients had a significantly higher median age (80 years) compared to KSS patients (70 years), indicating differing demographics in treatment approaches.
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Perioperative outcomes showed longer median length of stay for RNU (7.5 days) compared to KSS (3 days), with similar rates of postoperative complications.
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The study provides valuable insights for clinical decision-making regarding surgical options for upper tract urothelial carcinoma in solitary kidney patients.

World Journal Of Urology

by Francesco Ditonno, Alessandro Veccia, Gabriele Bignante, Zhenjie Wu, Linhui Wang, Firas Abdollah, Alex Stephens, Giuseppe Simone, Gabriele Tuderti, Randall Lee, Daniel D. Eun, Andres F. Correa, Ottavio De Cobelli, Matteo Ferro, Francesco Porpiglia, Daniele Amparore, Enrico Checcucci, Antonio Tufano, Roberto Contieri, Sisto Perdonà, Raj Bhanvadia, Vitaly Margulis, Stephan Brönimann, Nirmish Singla, James Porter, Saum Ghodoussipour, Andrea Minervini, Andrea Mari, Luca Lambertini, Alireza Ghoreifi, Omri Falik Nativ, Mark L. Gonzalgo, Daniel Sidhom, Chandru P. Sundaram, Reuben Ben-David, Ahmed Eraky, Reza Mehrazin, Takashi Yoshida, Hidefumi Kinoshita, Alireza Dehghanmanshadi, Soroush Rais-Bahrami, Margaret F. Meagher, Dhruv Puri, Ithaar H. Derweesh, Farshad S. Moghaddam, Hooman Djaladat, Riccardo Bertolo, Riccardo Autorino, Alessandro Antonelli
September 3, 2025

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