Efficacy and safety of an implantable tibial neuromodulation system for overactive bladder with urgency urinary incontinence: an open-label, single arm trial - Takeaways - MDSpire

Efficacy and safety of an implantable tibial neuromodulation system for overactive bladder with urgency urinary incontinence: an open-label, single arm trial

  • By

  • Fuyuan Zheng

  • Yongjun Guan

  • Weilin Fang

  • Tingting Lv

  • Jin Huang

  • Xin Song

  • Jianwei Lv

  • July 15, 2026

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  • 1

    The study evaluated the safety and efficacy of a domestically developed implantable tibial neuromodulation system for treating overactive bladder.

  • 2

    Ten participants underwent device implantation, with follow-up evaluations at 1, 3, and 6 months using bladder diaries and validated questionnaires.

  • 3

    At 6 months, the iTNS system achieved a 90% response rate, with 40% of patients experiencing ≥3 consecutive dry days.

  • 4

    Significant reductions in urgency urinary incontinence episodes were observed at 3 months and 6 months, improving quality of life.

  • 5

    The iTNS system demonstrated a favorable safety profile and effectively reduced or resolved urgency urinary incontinence symptoms.

Original Source(s)

Efficacy and safety of an implantable tibial neuromodulation system for overactive bladder with urgency urinary incontinence: an open-label, single arm trial

  • by Fuyuan Zheng, Yongjun Guan, Weilin Fang, Tingting Lv, Jin Huang, Xin Song, Jianwei Lv

  • July 15, 2026

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