Marked Reduction in HIV/HCV Coinfections in Iceland Following the TraP HepC Nationwide Hepatitis C Elimination Program - Takeaways - MDSpire

Marked Reduction in HIV/HCV Coinfections in Iceland Following the TraP HepC Nationwide Hepatitis C Elimination Program

  • By

  • Kara Hlynsdottir

  • Sigurdur Olafsson

  • Ubaldo Benitez Hernandez

  • Mar Kristjansson

  • Magnus Gottfredsson

  • December 31, 2025

  • 0 min

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  • 1

    The TraP HepC program in Iceland, initiated in 2016, significantly reduced HIV/HCV coinfection rates by over 85% by 2020.

  • 2

    Direct-acting antivirals (DAAs) replaced interferon treatments, leading to a cure rate increase from 45% to 88% among coinfected individuals.

  • 3

    The study identified 84 active HCV infections, resulting in 81 treatment initiations and 66 successful cures.

  • 4

    Despite the decrease in coinfection rates, the reinfection rate among treated individuals was 9.35 per 100 person-years.

  • 5

    Iceland achieved WHO targets for HCV elimination, diagnosing over 90% of infections and treating at least 80% of eligible individuals.

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