Predictors of cough resolution following endoscopic minimally invasive treatment in patients with GERD and chronic cough: a retrospective study - Takeaways - MDSpire

Predictors of cough resolution following endoscopic minimally invasive treatment in patients with GERD and chronic cough: a retrospective study

  • By

  • Xinhui Fang

  • Lida Zhang

  • Songze Ding

  • May 29, 2026

  • 0 min

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  • 1

    The study analyzed 200 GERD patients with chronic cough undergoing endoscopic minimally invasive treatment to identify cough resolution factors.

  • 2

    Key risk factors for persistent cough included ineffective esophageal motility, cough duration, DeMeester score, pepsin, and FeNO.

  • 3

    Secretory immunoglobulin A (SIgA) was identified as a protective factor against persistent cough post-treatment.

  • 4

    A nomogram model was developed based on identified risk factors, demonstrating good predictive efficacy with a ROC-AUC of 0.967.

  • 5

    The study emphasizes the importance of identifying high-risk GERD patients to improve treatment outcomes for chronic cough.

Original Source(s)

Predictors of cough resolution following endoscopic minimally invasive treatment in patients with GERD and chronic cough: a retrospective study

  • by Xinhui Fang, Lida Zhang, Songze Ding

  • May 29, 2026

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