Case Report: Cervical lymphadenitis resulting from Pseudomonas aeruginosa diagnosed by metagenomic next-generation sequencing - Takeaways - MDSpire

Case Report: Cervical lymphadenitis resulting from Pseudomonas aeruginosa diagnosed by metagenomic next-generation sequencing

  • By

  • Lihong Gao

  • Yang Wen

  • Xiaoyu Jing

  • May 18, 2026

  • 0 min

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  • 1

    An 11-year-old boy developed cervical lymphadenitis caused by Pseudomonas aeruginosa, diagnosed via metagenomic next-generation sequencing.

  • 2

    Traditional bacterial cultures were negative, highlighting the utility of metagenomic sequencing in identifying rare pathogens.

  • 3

    The patient initially received empiric treatment for common pathogens but required a lymph node biopsy due to worsening symptoms.

  • 4

    After diagnosis, the boy was treated with meropenem, leading to significant clinical improvement and eventual discharge.

  • 5

    Cervical lymphadenitis can be caused by Gram-negative opportunistic pathogens, emphasizing the need for advanced diagnostic techniques.

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