Integration of intraoperative ultrasound and depth-electrode electrocorticography for resection guidance in epilepsy surgery: technical workflow and feasibility - Takeaways - MDSpire

Integration of intraoperative ultrasound and depth-electrode electrocorticography for resection guidance in epilepsy surgery: technical workflow and feasibility

  • By

  • Luca Zanuttini

  • Elena Pasini

  • Lorenzo Ferri

  • Lidia Di Vito

  • Anna Scarabello

  • Francesca Bisulli

  • Matteo Martinoni

  • February 16, 2026

  • 0 min

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  • 1

    Approximately 30% of persons with epilepsy suffer from drug-resistant epilepsy, making surgical resection a critical treatment option.

  • 2

    Accurate delineation and complete resection of the epileptogenic zone are essential for successful surgical outcomes in epilepsy.

  • 3

    The combination of intraoperative ultrasound and depth-electrode electrocorticography enhances the precision of epileptogenic zone localization.

  • 4

    This review presents a structured workflow integrating depth-electrode iECoG and ioUS for tailored resection in drug-resistant epilepsy patients.

  • 5

    The approach aims to improve surgical decision-making by refining anatomical definitions of resection limits during epilepsy surgery.

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