Regional strain patterns in patients with mitral valve prolapse - Takeaways - MDSpire
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Strain Patterns Observed in Patients Diagnosed with Mitral Valve Prolapse

  • By

  • Jeffrey Ji-Peng Li

  • Shing Ching

  • Annette Aigner

  • Frank Edelmann

  • Stefanie Maria Werhahn

  • Rebecca Beyer

  • Jeanette Schulz-Menger

  • Jennifer Erley

  • Misael Estepa

  • Cyrill Meuwly

  • Ann-Sophie Eggers

  • Christian Stehning

  • Djawid Hashemi

  • Natalia Solowjowa

  • Christoph Klein

  • Ingo Hilgendorf

  • Sebastian Kelle

  • Patrick Doeblin

  • October 7, 2026

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  • 1

    Mitral valve prolapse affects approximately 2% to 3% of the population and can be complicated by significant regurgitation or ventricular arrhythmias.

  • 2

    CMR feature tracking quantifies regional myocardial strain using standard CMR sequences and has shown good intraobserver and interobserver reproducibility.

  • 3

    Prior CMR feature-tracking studies of strain in mitral valve prolapse reported inconsistent findings and often involved small cohorts or heterogeneous methods.

  • 4

    This retrospective study aimed to characterize global and regional longitudinal strain in the left ventricle, right ventricle, and left atrium in patients with mitral valve prolapse and controls.

  • 5

    The study included adults with preserved left ventricular ejection fraction and excluded participants with major cardiac conditions, including coronary disease and prior myocardial infarction.

Original Source(s)

Regional strain patterns in patients with mitral valve prolapse

  • by Jeffrey Ji-Peng Li, Shing Ching, Annette Aigner, Frank Edelmann, Stefanie Maria Werhahn, Rebecca Beyer, Jeanette Schulz-Menger, Jennifer Erley, Misael Estepa, Cyrill Meuwly, Ann-Sophie Eggers, Christian Stehning, Djawid Hashemi, Natalia Solowjowa, Christoph Klein, Ingo Hilgendorf, Sebastian Kelle, Patrick Doeblin

  • October 7, 2026

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