Fibromyalgia in cancer patients: a systematic review and clinical implications for integrated care - Takeaways - MDSpire

Fibromyalgia in cancer patients: a systematic review and clinical implications for integrated care

  • By

  • Melania Prete

  • Giuseppe Porciello

  • Elvira Palumbo

  • Sara Vitale

  • Maurizio Marchesini

  • Sabrina Bimonte

  • Francesco Del Prato

  • Arturo Cuomo

  • Marco Cascella

  • Maria Grimaldi

  • Natalia Russo

  • Assunta Luongo

  • Anna Crispo

  • June 11, 2026

  • 0 min

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  • 1

    Fibromyalgia (FM) is a significant comorbidity in cancer patients, complicating symptom assessment and management due to overlapping symptoms.

  • 2

    FM does not increase cancer risk but contributes to pain amplification, higher symptom burden, and reduced Health-Related Quality of Life (HRQoL) in oncology.

  • 3

    Pre-existing nociplastic pain features in FM patients are linked to premature discontinuation of oncological therapies, particularly endocrine treatments.

  • 4

    The review highlights a research gap in understanding FM in oncology, emphasizing the need for high-quality longitudinal studies.

  • 5

    An integrated, multidisciplinary treatment approach is essential for managing FM symptoms and optimizing oncological treatment effectiveness.

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