CURE: A Therapeutic Approach for Managing Chronic Inflammation Based on Phased Interventions

1

Chronic inflammation is a key factor in immune-mediated diseases, characterized by self-sustaining inflammatory circuits and cytokine redundancy.
2

The CURE framework proposes a phase-based therapeutic model focusing on CONTROL, UNLOAD and RESET, and EQUILIBRATE for managing chronic inflammation.
3

CURE emphasizes durable disease control and relapse prevention by aligning therapeutic intensity with the immune system's dynamic state.
4

The framework integrates evidence from various immune-mediated conditions, illustrating shared principles for effective disease management.
5

CURE reframes treatment from reactive symptom suppression to proactive, phase-specific immune stabilization for long-term health.

1