Interaction between depressive symptoms and social support on frailty risk among patients with chronic heart failure - Takeaways - MDSpire

Interaction between depressive symptoms and social support on frailty risk among patients with chronic heart failure

  • By

  • Mingjuan Guo

  • Yaohong Pan

  • Tingting Liao

  • Ruping Meng

  • June 25, 2026

  • 0 min

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  • 1

    The study investigated the interaction between depressive symptoms and social support on frailty in chronic heart failure patients.

  • 2

    A cross-sectional analysis of 380 CHF patients revealed a frailty prevalence of 41.3%.

  • 3

    Depressive symptoms and low social support were significantly associated with frailty, with odds ratios of 7.37 and 5.88, respectively.

  • 4

    A significant multiplicative interaction between depressive symptoms and social support was found, indicating a synergistic effect on frailty.

  • 5

    The study's findings highlight the need for longitudinal research to further explore the relationships among depressive symptoms, social support, and frailty.

Original Source(s)

Interaction between depressive symptoms and social support on frailty risk among patients with chronic heart failure

  • by Mingjuan Guo, Yaohong Pan, Tingting Liao, Ruping Meng

  • June 25, 2026

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