Malignant peripheral nerve sheath tumor of the ileocecal region: a case report - Takeaways - MDSpire

Malignant peripheral nerve sheath tumor of the ileocecal region: a case report

  • By

  • Yiqian Luo

  • Yuanyuan Wang

  • Rentong Liu

  • Yiwei Cheng

  • Chengjie Gan

  • Bing Li

  • July 3, 2026

  • 0 min

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  • 1

    Malignant peripheral nerve sheath tumor (MPNST) is a rare soft tissue sarcoma, with fewer than ten cases reported in the gastrointestinal tract.

  • 2

    This case represents the first reported instance of MPNST arising in the ileocecal region of a 62-year-old male patient.

  • 3

    Preoperative diagnosis of MPNST is challenging due to overlapping features with other colonic tumors, often leading to misdiagnosis.

  • 4

    The definitive diagnosis of colonic MPNST was confirmed through postoperative pathological examination and immunohistochemistry.

  • 5

    The patient underwent successful laparoscopic radical right hemicolectomy and showed no evidence of recurrence or metastasis at six-month follow-up.

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