24-h NIHSS score is the strongest prognostic predictor of 90-day outcome in cardioembolic stroke patients with anterior circulation occlusion after endovascular thrombectomy - Takeaways - MDSpire

24-h NIHSS score is the strongest prognostic predictor of 90-day outcome in cardioembolic stroke patients with anterior circulation occlusion after endovascular thrombectomy

  • By

  • Chen Yang

  • Yangxi Chen

  • Qingyan Liu

  • Ge Gong

  • Lei Guo

  • Yu Liu

  • Xinghu Zhang

  • May 13, 2026

  • 0 min

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  • 1

    The study analyzed 103 cardioembolic stroke patients with Anterior Circulation Occlusion post-endovascular thrombectomy.

  • 2

    24-hour NIHSS was identified as the strongest predictor of 90-day unfavorable functional outcomes in these patients.

  • 3

    ROC analysis showed 24-h NIHSS had an AUC of 0.850, outperforming baseline NIHSS and other change metrics.

  • 4

    The optimal cut-off value for 24-h NIHSS was determined to be ≥12, with 82.2% sensitivity and 75.6% specificity.

  • 5

    Combining 24-h NIHSS with other metrics did not enhance predictive performance compared to using 24-h NIHSS alone.

Original Source(s)

24-h NIHSS score is the strongest prognostic predictor of 90-day outcome in cardioembolic stroke patients with anterior circulation occlusion after endovascular thrombectomy

  • by Chen Yang, Yangxi Chen, Qingyan Liu, Ge Gong, Lei Guo, Yu Liu, Xinghu Zhang

  • May 13, 2026

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