Prospective randomised controlled trial to compare tissue reactions and scarring with polypropylene versus polyglactin 910 sutures in periocular skin - Takeaways - MDSpire

Prospective randomised controlled trial to compare tissue reactions and scarring with polypropylene versus polyglactin 910 sutures in periocular skin

  • By

  • Tessa Fayers

  • John S Vekinis

  • Laura Ah-Kye

  • David Parham

  • Priscilla Anketell

  • Justin Weir

  • Roger A’Hern

  • Ben Parkin

  • July 1, 2026

  • 0 min

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  • 1

    Different suture materials can provoke varying inflammatory reactions in host tissue, impacting surgical outcomes.

  • 2

    Prolene sutures may induce less histological inflammation than Vicryl in the short term, but both show good long-term scarring.

  • 3

    Some patients using Vicryl develop granulomas, potentially necessitating additional surgical intervention.

  • 4

    The study was a prospective, randomized trial conducted across two sites, focusing on patients with involutional entropion.

  • 5

    Histological reactions to Prolene and Vicryl sutures were compared, as previous studies had not addressed this directly.

Original Source(s)

Prospective randomised controlled trial to compare tissue reactions and scarring with polypropylene versus polyglactin 910 sutures in periocular skin

  • by Tessa Fayers, John S Vekinis, Laura Ah-Kye, David Parham, Priscilla Anketell, Justin Weir, Roger A’Hern, Ben Parkin

  • July 1, 2026

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