Prospective randomised controlled trial to compare tissue reactions and scarring with polypropylene versus polyglactin 910 sutures in periocular skin - Takeaways - MDSpire
Coming Soon: Introducing MDSpire News. Learn more
Conexiant’s news site is now MDSpire News. Learn more

Randomized Controlled Trial Evaluating Tissue Responses and Scarring in Periocular Skin Using Polypropylene Versus Polyglactin 910 Sutures

  • By

  • Tessa Fayers

  • John S Vekinis

  • Laura Ah-Kye

  • David Parham

  • Priscilla Anketell

  • Justin Weir

  • Roger A’Hern

  • Ben Parkin

  • July 1, 2026

Share

  • 1

    Different suture materials can provoke varying inflammatory reactions in host tissue, impacting surgical outcomes.

  • 2

    Prolene sutures may induce less histological inflammation than Vicryl in the short term, but both show good long-term scarring.

  • 3

    Some patients using Vicryl develop granulomas, potentially necessitating additional surgical intervention.

  • 4

    The study was a prospective, randomized trial conducted across two sites, focusing on patients with involutional entropion.

  • 5

    Histological reactions to Prolene and Vicryl sutures were compared, as previous studies had not addressed this directly.

Original Source(s)

Prospective randomised controlled trial to compare tissue reactions and scarring with polypropylene versus polyglactin 910 sutures in periocular skin

  • by Tessa Fayers, John S Vekinis, Laura Ah-Kye, David Parham, Priscilla Anketell, Justin Weir, Roger A’Hern, Ben Parkin

  • July 1, 2026

Related Content

GA Treatment Preferences

Survey questions what drives geographic atrophy treatment decisions for clinicians

  • August 4, 2026

  • 4 min
Toxoplasmosis: The Neglected Eye Threat

Global team urge WHO to formally recognize toxoplasmosis as a neglected tropical disease

  • August 18, 2026

  • 4 min
Dexamethasone may reduce severe ROP

Topical treatment numerically reduced progression to treatment-requiring retinopathy of prematurity in a randomized trial, although the primary endpoint was not met.