A triad of hypertension, heart failure, and glomerular injury in subacute Kawasaki disease: a case report and literature review - Takeaways - MDSpire

A triad of hypertension, heart failure, and glomerular injury in subacute Kawasaki disease: a case report and literature review

  • By

  • Qian Liu

  • Jing Liu

  • Ting Kang

  • Yuan Long

  • May 13, 2026

  • 0 min

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  • 1

    Kawasaki disease is the leading cause of acquired heart disease in children, characterized by acute systemic vasculitis.

  • 2

    The case study highlights a 7-year-old boy who developed acute heart failure, severe hypertension, and early kidney impairment during the subacute phase of Kawasaki disease.

  • 3

    Despite initial successful IVIG therapy and normalization of inflammatory markers, the patient exhibited significant vascular dysfunction.

  • 4

    This case suggests the need for revised monitoring during the subacute phase, including blood pressure and echocardiographic evaluations.

  • 5

    Persistent endothelial dysfunction can lead to long-term morbidity in Kawasaki disease, even after systemic inflammation resolves.

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