CHA2DS2-VA score for predicting ventricular arrhythmias and mortality in ICD patients with ischemic heart disease and dilated cardiomyopathy: results from a prospective cohort - Takeaways - MDSpire

CHA2DS2-VA score for predicting ventricular arrhythmias and mortality in ICD patients with ischemic heart disease and dilated cardiomyopathy: results from a prospective cohort

  • By

  • Benjamin Vögeli

  • Patrick Badertscher

  • Nicolas Schaerli

  • Christian Sticherling

  • Michael Kühne

  • Felix Mahfoud

  • Philipp Krisai

  • Beat Schär

  • May 13, 2026

  • 0 min

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  • 1

    The study evaluated the CHA2DS2-VA score's effectiveness in predicting mortality and ventricular arrhythmias in ICD patients with ischemic heart disease and dilated cardiomyopathy.

  • 2

    A total of 1,626 ICD recipients were analyzed, with a median follow-up of 7.5 years, revealing a 46% all-cause mortality rate.

  • 3

    Higher CHA2DS2-VA scores correlated with increased all-cause and cardiovascular mortality in both ischemic heart disease and dilated cardiomyopathy patients.

  • 4

    Each one-point increase in CHA2DS2-VA score raised the mortality risk significantly, indicating its utility in mortality risk stratification.

  • 5

    The CHA2DS2-VA score did not predict ventricular arrhythmias, suggesting it should not be used for arrhythmic risk assessment in these patients.

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