Association between aspirin use and decline in intrinsic capacity among community-dwelling elderly: a study based on the Lianyungang ICOPE pilot project - Takeaways - MDSpire

Association between aspirin use and decline in intrinsic capacity among community-dwelling elderly: a study based on the Lianyungang ICOPE pilot project

  • By

  • Yifang Wang

  • Lin Ma

  • Li Wang

  • Jing Gao

  • Rongli Lu

  • Miao Wen

  • Shixing Song

  • Quandong Wang

  • Yan Dong

  • June 24, 2026

  • 0 min

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  • 1

    The study investigates the relationship between aspirin use and intrinsic capacity deterioration in elderly individuals in Chinese communities.

  • 2

    A total of 250 participants were analyzed using propensity score matching to reduce baseline confounding factors.

  • 3

    Aspirin use alone was not significantly correlated with severe loss of intrinsic capacity but was linked to negative sensory function outcomes.

  • 4

    The combination of aspirin with ACEI or ARBs significantly reduced the incidence of severe loss of intrinsic capacity.

  • 5

    Sex variability was observed in the relationship between aspirin use and sensory function-related outcomes.

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